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Search results for "Imatinib"

An investigational new drug Sutent ( Sunitinib ) more than doubled survival and significantly reduced tumor growth and spread in patients with Imatinib-resistant gastrointestinal stromal tumors ( GIS ...


Researchers at the University of Michigan ( U-M ) Medical School, in collaboration with researchers at Harvard's Brigham and Women's Hospital, have discovered a recurring pattern of scrambled chromoso ...


Researchers at the Mayo Clinic Cancer Center report that Imatinib ( Glivec, Gleevec ), the drug used to treat patients with gastrointestinal stromal cancers ( GISTs ), is not likely to be effective fo ...


Axel Ullrich, at the Max Planck Institute of Biochemistry in Martinsried, Germany, already showed at the beginning of the 1990s that blocking blood vessel development in a tumour slows down its growth ...


Researchers at Dana-Farber Cancer Institute have identified a molecular interaction that triggers a particularly aggressive form of breast cancer, and suggest that attacking this target with selective ...


Researchers from The University of Texas M. D. Anderson Cancer Center reported in the Journal of the National Cancer Institute ( JNCI ) that Imatinib, a medication used to treat other types of cancer ...


A small pilot study from researchers at Dana-Farber Cancer Institute has shown that children with a rare digestive-tract cancer that is resistant to front-line therapy may benefit from a newer targete ...


Preliminary results from a large, randomized, placebo-controlled clinical trial for patients with primary gastrointestinal stromal tumor ( GIST ), a type of tumor usually found in the stomach or small ...


Researchers at Dana-Farber Cancer Institute have reported the first instance in which metastatic melanoma has been driven into remission by a targeted therapy. The report, published in the Journal of ...


Imatinib is the standard therapy for newly diagnosed CML patients. However, some patients develop resistance to the drug over time. In some patients, resistance develops in response to mutations in ...


Researchers at Dana-Farber Cancer Institute have reported the first instance in which metastatic melanoma has been driven into remission by a targeted therapy. The report, published in the Journal ...


Until now, only Imatinib ( Gleevec, Glivec ) and Sunitinib ( Sutent ) have proven clinical benefit in patients with gastrointestinal stromal tumours ( GIST ), but almost all metastatic GIST eventually ...


The application was for Regorafenib ( Stivarga ) to remain in the Cancer Drugs Fund ( CDF ) as treatment for patients with non-resectable or metastatic gastrointestinal stromal tumours ( GISTs ) who w ...